By Luigi Bolondi

In fresh years, the imaging-based analysis of mass liver lesions has turn into more and more advanced as a result quantity and morphological variability of lesions that glossy imaging recommendations are presently capable of show. If the sensitivity in detection has vastly elevated, characterisation has remained tricky and represents a severe problem for the clinician.

The availability of blood-pool distinction brokers for ultrasound (US), specifically second-generation US distinction brokers according to perfluorocarbon- or sulfur-hexafluoride-filled microbubbles, and the improvement of contrast-specific software program and applied sciences have unfolded new views either for the instant characterisation of any mass lesion detected within the liver and for expanding the sensitivity people within the detection of liver metastases.

Taking under consideration the nice influence of this new know-how on scientific perform, the ecu Federation of Societies for Ultrasound in drugs and Biology (EFSUMB) organised, in January 2004, in Rotterdam, a consensus assembly of specialists with the intention to increase guidance for using US distinction brokers within the prognosis of liver illnesses . those instructions, in addition to discussions of extra advances within the scientific software of contrast-enhanced harmonic US are provided during this publication through an the world over popular team of specialists. The ebook represents presents a major start line for medical implementation of this new diagnostic procedure.

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Additional info for Advances in Diagnostic Imaging: The Value of Contrast-Enhanced Ultrasound for Liver

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Surgical resection and liver transplantation still offer the best overall 5-year survival rate of approximately 30% [5]. However, only a limited number of patients, of less than 20%, can benefit from radical surgical treatments due to altered liver function and HCC extension and tumor volume. Percutaneous ablation using either ethanol injection or radiofrequency ablation (RFA) represents an alternative therapy to cure HCC when the number and size 50 Jean-Michel Correas et al. of the lesions is limited in Child A or B patients.

Karhunen PJ (1986) Benign hepatic tumours and tumour like conditions in men. J Clin Pathol 39:183-188 3. Jones EC, Chezmar JL, Nelson RC, Bernardino ME (1992) The frequency and significance of small (less than or equal to 15 mm) hepatic lesions detected by CT. AJR Am J Roentgenol 158(3):535-539 4. Schwartz LH, MD, Gandras EJ, Colangelo SM et al (1999) Prevalence and Importance of Small Hepatic Lesions Found at CT in Patients with Cancer. Radiology 210:71-74 5. Kinkel K, Lu Y, Both M et al (2002) Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET): a meta-analysis.

Monitoring of RF ablation of HCC 6 weeks after treatment. The lesion is the one described in Fig. 1. The ablated area covered entirely the site of the previously detected nodule. e CT confirmed the lack of persisting tumor 54 Jean-Michel Correas et al. of HCCs can be improved if they can be detected not only during arterial phase but also during the prolonged late phase (Figs. 3, 4). Development of specific imaging techniques and USCA with different properties should be directed to increase the impact of CEUS in cirrhosis.

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